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Among those genes, whose expression was upregulated in COPD patients, were genes involved in inflammation, while expression of genes involved in tissue remodeling and repair was markedly downregulated

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The actual model specification can be found in the technical model specification

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Studies have documented its capacity to stimulate collagen and glycosaminoglycan synthesis, accelerate wound healing, promote angiogenesis, exert antioxidant and anti-inflammatory effects, and modulate the expression of genes involved in tissue repair and regeneration

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Articular injection of 0.3 mg/ml GHK-Cu enhances some of the healing outcomes in a rat model of anterior cruciate ligament reconstruction (ACLR), and the treatment of GHK-Cu encapsulated in liposome significantly fasten burn wound healing in mice with scald wound [7, 16]

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